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N-Acetyl Semax Amidate peptide reference

Stabilised Semax variant with longer half-life. Same BDNF/NGF mechanism.

Last reviewed May 6, 2026 Human data Not FDA approved
Peppi reviewing N-Acetyl Semax Amidate notes
Default dose label600 mcg
Preferred routeIntranasal
Frequency label1× daily
Storage window30 days mixed

Evidence snapshot

Human data

Evidence maturityHuman data
Inferred from Semax parent literature; specific NA-Semax human data limited

Research chemical

Route map

How records are usually labeled

1 Intranasal
2 SubQ

Alternate nostrils.

Vial timeline

Storage cues to log

Before mixRefrigerate 2–8 °C; freeze long-term.
After mixRefrigerate 2–8 °C, use within 30 days.
Use-by cue30 days after mixing
Mixed vial window30 days
Use this as a record-keeping cue, not a replacement for product labeling.

Peppi workflow

From vial to review

Vial 5 mg vial
Dose 600 mcg
Route Intranasal
Review 30d storage

Peppi turns scattered dose, vial, route, storage, note, and report details into one record trail.

Educational reference only

This page helps you understand what to track for N-Acetyl Semax Amidate. It is not medical advice, a prescription, or a recommendation to use this peptide. Discuss dose, route, timing, storage, and safety with a qualified healthcare professional.

Overview

N-Acetyl Semax Amidate (NA-Semax) is a stability-modified analog of Semax with N-terminal acetylation and C-terminal amidation. The modifications resist peptidase degradation, extending the effective half-life from minutes to hours and producing more sustained BDNF/NGF effects. Same therapeutic claims as Semax; sold as research-only.

Also known as: NA-Semax, NASA.

Cognitive enhancement (focus, memory)Neuroprotection researchConvenient single-daily-dose alternative to Semax

Mechanism and timing snapshot

Same as Semax — modulates BDNF/NGF expression, monoaminergic systems. N-terminal acetylation and C-terminal amidation extend half-life vs the parent peptide.

Onset label10 min
Catalog onset field, when available.
Half-life label4 hr
~3–4 hours plasma (vs ~20 min for Semax); CNS effects longer
Duration label8 hr
Catalog duration field, when available.
intranasal Moderate to high
subQ High
oral Negligible

Tracking defaults

These values come from Peppi's catalog so records can be prefilled consistently. They should be reviewed against your clinician's instructions before logging real-world use.

Catalog default dose600 mcg
Catalog dose range300 mcg - 900 mcg
Default routeIntranasal
Frequency label1× daily
Best time labelMorning to avoid sleep disruption.
Food noteNone.

Catalog protocol note

300–600 mcg intranasal once daily for 7–14 days. Single daily dose works due to longer half-life.

Routes and site notes

Available route labelsIntranasal, SubQ
Preferred route labelIntranasal
Common site labelsBoth nostrils, alternating
Site rotation noteAlternate nostrils.

Chemistry

SequenceAc-Met-Glu-His-Phe-Pro-Gly-Pro-NH2
Amino acids7
Molecular formulaC39H53N9O10S
Molecular weight854 Da

Vial, reconstitution, and storage

Supply formLyophilized powder or pre-formulated nasal spray
Typical vial size5 mg
DiluentBacteriostatic water or saline
Diluent volume5 mL
Concentration note5 mg in 5 mL → 0.6 mL = 600 mcg per dose.
Before reconstitutionRefrigerate 2–8 °C; freeze long-term.
After reconstitutionRefrigerate 2–8 °C, use within 30 days.
Reconstituted shelf life30 days
Light sensitiveNo
Freeze/thaw warningYes

Safety notes

Common and rare side effects listed in the catalog

  • Same as Semax
  • Mildly stimulating
  • Nasal irritation
  • Insomnia if dosed late
  • Mild restlessness

Contraindications and warnings

  • Pregnancy
  • Severe psychiatric disorders without clinician oversight
  • Sold as research-only; not approved anywhere.

Other considerations

  • Longer half-life than Semax — single daily dose practical.
  • Same subjective variability as Semax — some users feel strong focus, others minimal.

Evidence and regulatory context

Evidence levelInferred from Semax parent literature; specific NA-Semax human data limited
FDA approvedNo
Regulatory statusResearch chemical
Prescription requiredNo
Approved countriesNot listed

Stacking and cycle notes

Stacks well withNot listed
Avoid combining notesemax (redundant)
Typical cycle label1–4
Typical break label1–2
Cycle guidanceCourse-based use; short cycles.

Tracking tips

  • Single daily dose due to extended half-life — convenient vs Semax.
  • Morning dosing to avoid sleep disruption.
  • Subjective effects are subtle; assess over a 1–2 week course.

References

Track it in Peppi

Keep N-Acetyl Semax Amidate records organized.

Use Peppi for dose logs, vial inventory, storage dates, reminders, journal notes, photos, and clinician-ready reports.

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FAQ

What should I track for N-Acetyl Semax Amidate?

Track the peptide name, dose amount and unit, route, vial label, timing, reconstitution or expiration dates, storage notes, and any symptoms or questions for clinician review.

Does Peppi tell me how to use N-Acetyl Semax Amidate?

No. Peppi organizes educational reference and your own records. Protocol decisions should come from a qualified healthcare professional.

Can I export N-Acetyl Semax Amidate records?

Peppi is designed to keep dose logs, vial inventory, journal notes, and reports easier to review and export.

Last reviewed: May 6, 2026