PeppiLibrary

Immune

Thymopentin peptide reference

Pentapeptide active fragment of thymopoietin. Immune restoration in immunocompromised states.

Last reviewed May 6, 2026 Human data Not FDA approved
Peppi reviewing Thymopentin notes
Default dose label50 mg
Preferred routeSubQ
Frequency label3× weekly
Storage window7 days mixed

Evidence snapshot

Human data

Evidence maturityHuman data
Approved in Italy historically; multiple older clinical trials

Prescription medication abroad; research/off-label in US

Route map

How records are usually labeled

1 SubQ
2 IM
3 IV

Rotate sites for repeated dosing.

Vial timeline

Storage cues to log

Before mixRefrigerate 2–8 °C.
After mixUse immediately per label; off-label compounded vials may be refrigerated for 7 days.
Use-by cue7 days after mixing
Mixed vial window7 days
Use this as a record-keeping cue, not a replacement for product labeling.

Peppi workflow

From vial to review

Vial 50 mg vial
Dose 50 mg
Route SubQ
Review 7d storage

Peppi turns scattered dose, vial, route, storage, note, and report details into one record trail.

Educational reference only

This page helps you understand what to track for Thymopentin. It is not medical advice, a prescription, or a recommendation to use this peptide. Discuss dose, route, timing, storage, and safety with a qualified healthcare professional.

Overview

Thymopentin is the synthetic 5-amino-acid biologically active fragment (residues 32–36) of thymopoietin, a thymic hormone. It mimics the immune-modulating activity of the parent protein with higher safety and easier production. Approved historically in Italy for immune-deficient states; widely used in HIV-era research; not FDA-approved.

Also known as: TP-5, Timunox, Timopentin.

Primary or acquired immunodeficiency (approved abroad)Adjuvant immune support in chronic infectionsRheumatoid arthritis (historic European indication)

Mechanism and timing snapshot

Promotes T-cell maturation and differentiation; modulates Th1/Th2 balance; enhances natural killer cell activity. Acts on a thymopoietin-specific cell surface site.

Onset labelNot listed
Catalog onset field, when available.
Half-life label3 min
Plasma half-life ~30 seconds; downstream immune effects persist days
Duration label72 hr
Catalog duration field, when available.
subQ High
IM High
oral Negligible

Tracking defaults

These values come from Peppi's catalog so records can be prefilled consistently. They should be reviewed against your clinician's instructions before logging real-world use.

Catalog default dose50 mg
Catalog dose range25 mg - 50 mg
Default routeSubQ
Frequency label3× weekly
Best time labelSame days each week.
Food noteNone.

Catalog protocol note

50 mg subQ 3× per week (label dose for chronic immune deficiency).

Routes and site notes

Available route labelsSubQ, IM, IV
Preferred route labelSubQ
Common site labelsAbdomen, Thigh
Site rotation noteRotate sites for repeated dosing.

Chemistry

SequenceArg-Lys-Asp-Val-Tyr
Amino acids5
Molecular formulaC30H49N9O9
Molecular weight679.77 Da

Vial, reconstitution, and storage

Supply formLyophilized powder (single-use vial in commercial form)
Typical vial size50 mg
DiluentSterile water for injection
Diluent volume1 mL
Concentration note50 mg vial in 1 mL → entire vial = full dose. Single-use.
Before reconstitutionRefrigerate 2–8 °C.
After reconstitutionUse immediately per label; off-label compounded vials may be refrigerated for 7 days.
Reconstituted shelf life7 days
Light sensitiveYes
Freeze/thaw warningYes

Safety notes

Common and rare side effects listed in the catalog

  • Generally extremely well-tolerated
  • Mild injection-site reactions
  • Transient flu-like symptoms early in use

Contraindications and warnings

  • Active autoimmune disease
  • Active immunosuppressive therapy where suppression is the goal
  • Not FDA-approved in the US.

Other considerations

  • Older immune-modulatory peptide with extensive Italian and European clinical track record.
  • Pairs conceptually with Thymosin Alpha-1 in immune stacks.
  • Effects are cumulative — months not days.

Evidence and regulatory context

Evidence levelApproved in Italy historically; multiple older clinical trials
FDA approvedNo
Regulatory statusPrescription medication abroad; research/off-label in US
Prescription requiredYes
Approved countriesItaly (historic), China

Stacking and cycle notes

Stacks well withthymosin-alpha-1
Avoid combining noteActive immunosuppressive therapy where opposed to goal
Typical cycle label12–52
Typical break labelPer clinician
Cycle guidanceLong courses are typical for immune deficiency; short courses for acute support.

Tracking tips

  • Pairs with Thymosin Alpha-1 in immune-stack research protocols.
  • Effects are cumulative over months — short courses won't show much.
  • If on immunosuppressants for autoimmune or transplant reasons, discuss with prescriber.

References

Track it in Peppi

Keep Thymopentin records organized.

Use Peppi for dose logs, vial inventory, storage dates, reminders, journal notes, photos, and clinician-ready reports.

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FAQ

What should I track for Thymopentin?

Track the peptide name, dose amount and unit, route, vial label, timing, reconstitution or expiration dates, storage notes, and any symptoms or questions for clinician review.

Does Peppi tell me how to use Thymopentin?

No. Peppi organizes educational reference and your own records. Protocol decisions should come from a qualified healthcare professional.

Can I export Thymopentin records?

Peppi is designed to keep dose logs, vial inventory, journal notes, and reports easier to review and export.

Last reviewed: May 6, 2026