PeppiLibrary

Growth Hormone

GHRP-2 peptide reference

Older GH secretagogue. Strong pulse but raises cortisol and prolactin.

Last reviewed May 6, 2026 Research Not FDA approved
Peppi reviewing GHRP-2 notes
Default dose label200 mcg
Preferred routeSubQ
Frequency label1–3× daily, on empty stomach
Storage window30 days mixed

Evidence snapshot

Research

Evidence maturityResearch
Approved as diagnostic agent in Japan/South Korea; research-only elsewhere

Diagnostic prescription medication (Japan, South Korea); research chemical elsewhere

Route map

How records are usually labeled

1 SubQ
2 IM
3 Intranasal

Rotate within the abdomen.

Vial timeline

Storage cues to log

Before mixRefrigerate 2–8 °C; freeze long-term.
After mixRefrigerate 2–8 °C, use within 30 days.
Use-by cue30 days after mixing
Mixed vial window30 days
Use this as a record-keeping cue, not a replacement for product labeling.

Peppi workflow

From vial to review

Vial 5 mg vial
Dose 200 mcg
Route SubQ
Review 30d storage

Peppi turns scattered dose, vial, route, storage, note, and report details into one record trail.

Educational reference only

This page helps you understand what to track for GHRP-2. It is not medical advice, a prescription, or a recommendation to use this peptide. Discuss dose, route, timing, storage, and safety with a qualified healthcare professional.

Overview

GHRP-2 is a synthetic hexapeptide ghrelin-receptor agonist that triggers a robust GH pulse. Compared to Ipamorelin, it produces a larger GH spike but at the cost of meaningful elevation in cortisol, prolactin, and ACTH. Approved as a diagnostic agent for GH deficiency in Japan and South Korea.

Also known as: Pralmorelin, KP-102.

GH stimulation testing (diagnostic)Recovery and sleep qualityLean-mass support stacked with GHRH analogs

Mechanism and timing snapshot

Ghrelin/GHS-R1a receptor agonist on pituitary somatotrophs; less selective than Ipamorelin — also activates pathways that raise cortisol, prolactin, and ACTH.

Onset label15 min
Catalog onset field, when available.
Half-life label30 min
Plasma half-life ~15–60 min
Duration label2 hr
Catalog duration field, when available.
subQ High
intranasal Moderate (~30–60%)
oral Negligible

Tracking defaults

These values come from Peppi's catalog so records can be prefilled consistently. They should be reviewed against your clinician's instructions before logging real-world use.

Catalog default dose200 mcg
Catalog dose range100 mcg - 300 mcg
Default routeSubQ
Frequency label1–3× daily, on empty stomach
Best time labelPre-bed and/or post-workout, on empty stomach.
Food noteAvoid food and high insulin within 30–60 min before or after dosing.

Catalog protocol note

100–300 mcg subQ 1–3× daily on empty stomach. Often paired with a GHRH analog like Mod GRF 1-29.

Routes and site notes

Available route labelsSubQ, IM, Intranasal
Preferred route labelSubQ
Common site labelsAbdomen
Site rotation noteRotate within the abdomen.

Chemistry

SequenceD-Ala-D-2-Nal-Ala-Trp-D-Phe-Lys-NH2
Amino acids6
Molecular formulaC45H55N9O6
Molecular weight817.97 Da

Vial, reconstitution, and storage

Supply formLyophilized powder
Typical vial size5 mg
DiluentBacteriostatic water
Diluent volume2 mL
Concentration note5 mg in 2 mL → 0.08 mL = 200 mcg (8 units on a 100-unit insulin syringe).
Before reconstitutionRefrigerate 2–8 °C; freeze long-term.
After reconstitutionRefrigerate 2–8 °C, use within 30 days.
Reconstituted shelf life30 days
Light sensitiveYes
Freeze/thaw warningYes

Safety notes

Common and rare side effects listed in the catalog

  • Hunger spike
  • Mild flushing
  • Vivid dreams pre-bed
  • Water retention
  • Numbness in extremities
  • Cortisol elevation symptoms (anxiety, sleep disturbance)

Contraindications and warnings

  • Active malignancy
  • Cushing's syndrome
  • Sold as research-only in the US — not FDA-approved for human use.

Other considerations

  • Cleaner alternative: Ipamorelin (less cortisol/prolactin elevation).
  • Hunger spike is more pronounced than Ipamorelin but less than GHRP-6.

Evidence and regulatory context

Evidence levelApproved as diagnostic agent in Japan/South Korea; research-only elsewhere
FDA approvedNo
Regulatory statusDiagnostic prescription medication (Japan, South Korea); research chemical elsewhere
Prescription requiredYes
Approved countriesJapan, South Korea

Stacking and cycle notes

Stacks well withcjc-1295
Avoid combining noteOther ghrelin agonists simultaneously
Typical cycle label8–12
Typical break label4
Cycle guidanceCycle to maintain receptor sensitivity; tachyphylaxis develops faster than with Ipamorelin.

Tracking tips

  • If cortisol/prolactin elevation matters to you, use Ipamorelin instead.
  • Pairs with Mod GRF 1-29 (no-DAC CJC-1295) for synergistic pulse.
  • Strict empty-stomach window is essential.

References

Track it in Peppi

Keep GHRP-2 records organized.

Use Peppi for dose logs, vial inventory, storage dates, reminders, journal notes, photos, and clinician-ready reports.

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FAQ

What should I track for GHRP-2?

Track the peptide name, dose amount and unit, route, vial label, timing, reconstitution or expiration dates, storage notes, and any symptoms or questions for clinician review.

Does Peppi tell me how to use GHRP-2?

No. Peppi organizes educational reference and your own records. Protocol decisions should come from a qualified healthcare professional.

Can I export GHRP-2 records?

Peppi is designed to keep dose logs, vial inventory, journal notes, and reports easier to review and export.

Last reviewed: May 6, 2026